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APOB 抗体 (AA 592-689)

APOB 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126530
发货至: 中国
  • 抗原 See all APOB 抗体
    APOB (Apolipoprotein B (APOB))
    抗原表位
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 592-689
    适用
    • 89
    • 24
    • 22
    • 6
    • 3
    宿主
    • 60
    • 35
    • 13
    • 2
    • 1
    小鼠
    克隆类型
    • 74
    • 35
    单克隆
    标记
    • 42
    • 21
    • 17
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOB antibody is un-conjugated
    应用范围
    • 63
    • 47
    • 33
    • 16
    • 16
    • 13
    • 10
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Human recombinant APOB protein fragment (around aa 592-689) (exact sequence is proprietary)
    亚型
    IgG1
    Top Product
    Discover our top product APOB Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human liver or kidney tissue.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    APOB (Apolipoprotein B (APOB))
    别名
    APOB (APOB 产品)
    别名
    FLDB antibody, LDLCQ4 antibody, Ac1-060 antibody, Apo B-100 antibody, ApoB-100 antibody, ApoB-48 antibody, AI315052 antibody, apob-100 antibody, apob-48 antibody, APOB-100 antibody, ApoB(100) antibody, APOB antibody, apolipoprotein B antibody, APOB antibody, Apob antibody
    背景
    ApoB 100, ApoB 48, Apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, FLDB, LDLCQ4,Apolipoprotein B / APOB
    Cellular localisation: Cytoplasm. Secreted.
    分子量
    512kDa
    基因ID
    338, 120759
    UniProt
    P04114
    途径
    Lipid Metabolism
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