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APOA1 抗体 (AA 83-167)

This anti-APOA1 antibody is a 小鼠 单克隆 antibody detecting APOA1 in IHC (f). Suitable for 人.
产品编号 ABIN7126527
发货至: 中国

Quick Overview for APOA1 抗体 (AA 83-167) (ABIN7126527)

抗原

See all APOA1 抗体
APOA1 (Apolipoprotein A-I (APOA1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This APOA1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 83-167

    特异性

    Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Human recombinant APOA1 protein fragment (around aa 83-167) (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human liver.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    APOA1 (Apolipoprotein A-I (APOA1))

    别名

    APOA1

    背景

    ApoA1, Brp14, high density lipoprotein uptake, Ltw1, Lvtw1, Sep1, Sep2,Apolipoprotein A1 / APOA1
    Cellular localisation: Secreted.

    分子量

    28kDa

    基因ID

    335, 93194

    UniProt

    P02647

    途径

    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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