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Recombinant FOXP1 抗体 (AA 350-450)

This anti-FOXP1 antibody is a 兔 单克隆 antibody detecting FOXP1 in IHC (f). Suitable for 人.
产品编号 ABIN7126477
发货至: 中国

Quick Overview for Recombinant FOXP1 抗体 (AA 350-450) (ABIN7126477)

抗原

See all FOXP1 抗体
FOXP1 (Forkhead Box P1 (FOXP1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This FOXP1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 350-450

    特异性

    Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff ( 80 % ) for FOXP1 is needed to achieve high specificity for the ABC subtype.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa350-450) of human FOXP1 protein (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human tonsil or colon.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    FOXP1 (Forkhead Box P1 (FOXP1))

    别名

    FOXP1

    背景

    Fork head related protein like B, Forkhead box protein P1 (FOXP1), Glutamine rich factor 1, hFKH1B, HSPC215, QRF1,FOXP1 (Transcription Factor)
    Cellular localisation: Nucleus.

    分子量

    75kDa

    基因ID

    27086

    UniProt

    Q9H334

    途径

    Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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