Recombinant FOXP1 抗体 (AA 350-450)
Quick Overview for Recombinant FOXP1 抗体 (AA 350-450) (ABIN7126476)
抗原
See all FOXP1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-450
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特异性
- Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff ( 80 % ) for FOXP1 is needed to achieve high specificity for the ABC subtype.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa350-450) of human FOXP1 protein (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil or colon.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- FOXP1 (Forkhead Box P1 (FOXP1))
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别名
- FOXP1
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背景
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Fork head related protein like B, Forkhead box protein P1 (FOXP1), Glutamine rich factor 1, hFKH1B, HSPC215, QRF1,FOXP1 (Transcription Factor)
Cellular localisation: Nucleus. -
分子量
- 75kDa
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基因ID
- 27086
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UniProt
- Q9H334
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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