GCET2 抗体 (AA 1-200)
Quick Overview for GCET2 抗体 (AA 1-200) (ABIN7126453)
抗原
See all GCET2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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特异性
- Recognizes a protein of kDa, which is identified as HGAL. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (178 Amino acid residues from around aa1-200) of human HGAL protein
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亚型
- IgG1
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anti-Germinal Center Expressed Transcript 2 (GCET2) (AA 1-178) antibody
GCET2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Germinal Center Expressed Transcript 2 (GCET2) (AA 31-130) antibodyGCET2 适用: 小鼠 ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Germinal Center Expressed Transcript 2 (GCET2) (AA 1-178) antibodyGCET2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Germinal Center Expressed Transcript 2 (GCET2) antibodyGCET2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Germinal Center Expressed Transcript 2 (GCET2) antibodyGCET2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Germinal Center Expressed Transcript 2 (GCET2) (AA 1-178) antibodyGCET2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Germinal Center Expressed Transcript 2 (GCET2) (C-Term) antibodyGCET2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Daudi, Raji or U266 cells. Human lymphocytes. Human lymph node, tonsil or testis.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- GCET2 (Germinal Center Expressed Transcript 2 (GCET2))
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别名
- GCSAM
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背景
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GCAT2, GCET2 germinal center expressed transcript 2, Germinal center associated lymphoma (hGAL), Germinal center B-cell-expressed transcript 2 protein, Germinal center-associated signaling and motility protein,HGAL (Human Germinal Center Associated Lymphoma Marker)
Cellular localisation: Cytoplasm. Cell surface. -
分子量
- 21kDa
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基因ID
- 257144, 49614
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UniProt
- Q8N6F7
抗原
-
