CD15 抗体
Quick Overview for CD15 抗体 (ABIN7126452)
抗原
See all CD15 (FUT4) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on 95 % of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Purified neutrophils from normal human peripheral blood
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亚型
- IgM
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应用备注
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Known_Application: Immunofluorescence (1-2ug/ml); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: U937 cells. Reed-Sternberg's cells in Hodgkin's lymphoma
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD15 (FUT4) (Fucosyltransferase 4 (Alpha (1,3) Fucosyltransferase, Myeloid-Specific) (FUT4))
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别名
- FUT4
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背景
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3 Fucosyl N Acetyl Lactosamine, Alpha (1,3) Fucosyltransferase, Alpha 13 fucosyltransferase FucT, ELAM Ligand Fucosyltransferase, ELFT, FCT3A, Fuc-TIV, Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific, Fucosyltransferase 4, Galactoside 3 L Fucosyltransferase, Lewis X, LeX, SSEA1, Stage Specific Embryonic Antigen 1,CD15 / FUT4 (Reed-Sternberg Cell Marker)
Cellular localisation: Cell surface and granular paranuclear -
分子量
- ~220kDa
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基因ID
- 2526, 654379
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UniProt
- P22083
抗原
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