Elastase 3B 抗体 (AA 82-238)
Quick Overview for Elastase 3B 抗体 (AA 82-238) (ABIN7126431)
抗原
See all Elastase 3B (ELA3B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 82-238
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特异性
- This MAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant human CELA3B protein fragment (around aa 82-238) (exact sequence is proprietary)
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亚型
- IgG3
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anti-Elastase 3B, Pancreatic (ELA3B) (AA 82-238) antibody
ELA3B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CELA3B-1257 unconjugated
anti-Elastase 3B, Pancreatic (ELA3B) (AA 82-238) antibodyELA3B 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal CELA3B-1757 unconjugated
anti-Elastase 3B, Pancreatic (ELA3B) (AA 82-238) antibodyELA3B 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-410M unconjugated Recombinant Antibody
anti-Elastase 3B, Pancreatic (ELA3B) (AA 28-267) antibodyELA3B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastase 3B, Pancreatic (ELA3B) (AA 19-270) antibodyELA3B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H3 unconjugated
anti-Elastase 3B, Pancreatic (ELA3B) (AA 82-238) antibodyELA3B 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal rCELA3B-1811 unconjugated Recombinant Antibody
anti-Elastase 3B, Pancreatic (ELA3B) (AA 82-238) antibodyELA3B 适用: 人 IHC, StM 宿主: 兔 Monoclonal CELA3B-2809R unconjugated Recombinant Antibody
anti-Elastase 3B, Pancreatic (ELA3B) (AA 82-238) antibodyELA3B 适用: 人, 小鼠, 大鼠 ELISA, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal CELA3B-1257 unconjugated
anti-Elastase 3B, Pancreatic (ELA3B) (AA 29-270) antibodyELA3B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Elastase 3B, Pancreatic (ELA3B) (AA 19-270) antibodyELA3B 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL),ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA)Optimal dilution for a specific application should be determined.
Positive_Control: Panc-28 or PANC1 cells. Pancreas
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))
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别名
- CELA3B
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背景
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Chymotrypsin like elastase family member 3B (CELA3B), ELA3B, Elastase IIIB, Protease E,CELA3B / ELA3B (Pancreatic Function Marker)
Cellular localisation: Cytoplasmic -
分子量
- ~17kDa
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基因ID
- 23436, 728752
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UniProt
- P08861
抗原
-
