SIRT2 抗体
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- 抗原 See all SIRT2 抗体
- SIRT2 (Sirtuin 2 (SIRT2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SIRT2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- The silent information regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. In S. cerevisiae, Sir2p deacetylates histones in a NAD-dependent manner, which regulates silencing at the telomeric, rDNA and silent mating-type loci. Sir2p is the founding member of a large family, designated sirtuins, which contain a conserved catalytic domain. The human homologs, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. SIRT proteins may function via mono-ADP-ribosylation of proteins. SIRT2 contains a 323 amino acid catalytic core domain with a NAD-binding domain and a large groove which is the likely site of catalysis.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human SIRT2 protein
- 亚型
- IgG1
- Top Product
- Discover our top product SIRT2 Primary Antibody
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anti-Sirtuin 2 (SIRT2) (AA 288-389) antibody
SIRT2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 128-227) antibodySIRT2 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-Sirtuin 2 (SIRT2) (AA 165-187), (Middle Region) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 28-303) antibodySIRT2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 65-340) antibodySIRT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 1D4-H11-H11 unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 2 (SIRT2) (AA 275-389) antibodySIRT2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5H11H9 unconjugated
anti-Sirtuin 2 (SIRT2) (C-Term) antibodySIRT2 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, MCF-7 or U-87 cells.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SIRT2 (Sirtuin 2 (SIRT2))
- 别名
- SIRT2 (SIRT2 产品)
- 背景
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NAD-dependent deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, Silencing information regulator 2 like, Silent information regulator 2, SIR2, SIR2 like protein 2, Sirtuin type 2,SIRT2
Cellular localisation: Cytoplasm > cytoskeleton. Colocalizes with microtubules. - 分子量
- 43kDa
- 基因ID
- 22933, 466693
- UniProt
- Q8IXJ6
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