FABP5 抗体 (AA 1-200)
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北京 101111
Quick Overview for FABP5 抗体 (AA 1-200) (ABIN7126381)
抗原
See all FABP5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-200
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原理
- Fibroblast Activation Protein Alpha / FAP-1 Antibody
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特异性
- FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is colocalized with MMP-1 and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility.
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 1-200) of human FAP protein (exact sequence is proprietary)
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亚型
- IgG2c, kappa
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anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 1-135) antibody
FABP5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) antibodyFABP5 适用: 人, 小鼠, 大鼠 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 1-132) antibodyFABP5 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) antibodyFABP5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CPTC-FABP5-3 unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 10-23) antibodyFABP5 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 21-120) antibodyFABP5 适用: 小鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 1-100) antibodyFABP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 10-23), (N-Term) antibodyFABP5 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 2-135) antibodyFABP5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5) (AA 1-135) antibodyFABP5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human uterus, colon or pancreas. Fibroblast specific.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))
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别名
- FABP5
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背景
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170 kDa melanoma membrane-bound gelatinase, DPPIV, FAP, FAPA, Fibroblast activation protein alpha, Integral membrane serine protease, Seprase
colon or pancreas. Fibroblast specific., Human uterus
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分子量
- 88kDa
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基因ID
- 2191, 654370
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UniProt
- Q12884
抗原
-
