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FABP5 抗体

The 小鼠 单克隆 anti-FABP5 antibody (Clone CPTC-FABP5-3) (ABIN6939368) specifically detects FABP5 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN6939368
发货至: 中国
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Quick Overview for FABP5 抗体 (ABIN6939368)

抗原

See all FABP5 抗体
FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FABP5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

CPTC-FABP5-3
  • 原理

    FABP5 (Marker of Metastatic Potential in Colorectal Cancer) Antibody

    特异性

    This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human full-length FABP5 protein

    亚型

    IgG2a, kappa
  • 应用备注

    Positive Control: MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.

    Known Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

    别名

    FABP5

    背景

    FABP5, E-FABP, EFABP, PA-FABP, PAFABP

    HeLa or HEK-293 cells. Keratinocytes, highly expressed in psoriatic skin., Molt-4, Raji

    分子量

    15.4kDa

    基因ID

    2171, 408061

    UniProt

    Q01469
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