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Recombinant FABP5 抗体

This anti-FABP5 antibody is a 小鼠 单克隆 antibody detecting FABP5 in WB 和 IHC (f). Suitable for 人.
产品编号 ABIN7126379
发货至: 中国

Quick Overview for Recombinant FABP5 抗体 (ABIN7126379)

抗原

See all FABP5 抗体
FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FABP5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus. FABP5 is also associated with poor survival in triple-negative breast cancer. Additionally, FABP5 gene is upregulated in colorectal cancer cells compared to normal colon cells in a manner that correlates with disease stage and that FABP5 significantly promotes colorectal cancer cell growth and metastatic potential.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant human full-length FABP5 protein

    亚型

    IgG1
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: MOLT-4, HeLa or HEK-293 cells.Keratinocytes, highly expressed in psoriatic skin.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    FABP5 (Fatty Acid Binding Protein 5 (Psoriasis-Associated) (FABP5))

    别名

    FABP5

    背景

    FABP5, E-FABP, EFABP, PA-FABP, PAFABP,FABP5 (Marker of Metastatic Potential in Colorectal Cancer)
    Cellular localisation: Nuclear. Cytoplasmic.

    分子量

    15.4kDa

    基因ID

    2171, 408061

    UniProt

    Q01469
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