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FABP4 抗体 (AA 1-132)

The 小鼠 单克隆 anti-FABP4 antibody (ABIN7126366) specifically detects FABP4 in IHC (f). The antibody is reactive with 人 samples.
产品编号 ABIN7126366
发货至: 中国
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Quick Overview for FABP4 抗体 (AA 1-132) (ABIN7126366)

抗原

See all FABP4 抗体
FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FABP4 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

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    AA 1-132

    特异性

    Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21.13, and encodes a 132 amino acid protein. A-FABP protein comprises approximately 1 % of the total cytosolic protein in human adipose tissue.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-132) of human FABP4 protein (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human adipose tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

    别名

    FABP4

    背景

    3T3-L1 lipid-binding protein, 422/aP2, A-FABP, Adipocyte lipid binding protein, Adipocyte protein AP2, Adipocyte-type fatty acid-binding protein, AFABP, ALBP/Ap2, aP2, Epididymis secretory protein Li 104, Fatty acid binding protein 4 adipocyte, HEL S 104, Lbpl, Myelin P2 protein homolog, P15, P2 adipocyte protein, Protein 422,Fatty Acid Binding Protein 4 (FABP4)
    Cellular localisation: Cytoplasm. Nucleus.

    分子量

    15kDa

    基因ID

    2167, 391561

    UniProt

    P15090

    途径

    Brown Fat Cell Differentiation
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