ESR2 抗体 (C-Term)
Quick Overview for ESR2 抗体 (C-Term) (ABIN7126353)
抗原
See all ESR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This MAb recognizes the estrogen receptor beta 2 isoform, expressed in cell nuclei of a range of human tissues including ovary, placenta, testis and vas deferens. No cross-reactivity is seen with estrogen receptor beta 1 isoform. This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- A synthetic peptide (CGMKMETLLPEATMEQ ) from the C terminus of the human estrogen receptor beta 2 isomer
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亚型
- IgG1
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anti-Estrogen Receptor 2 (ESR2) (C-Term) antibody
ESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ERb455 unconjugated
anti-Estrogen Receptor 2 (ESR2) (N-Term) antibodyESR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (C-Term) antibodyESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal ERb455 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 201-300) antibodyESR2 适用: 人, 小鼠, 大鼠, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 46-530) antibodyESR2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 211-240) antibodyESR2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41114 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 417-428) antibodyVerified ESR2 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 22-121) antibodyESR2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Estrogen Receptor 2 (ESR2) (pSer105) antibodyESR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 1-280) antibodyESR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (2-4 μg/million cells), Immunofluorescence (2-4 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 cells. Human testis tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- ESR2 (Estrogen Receptor 2 (ESR2))
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别名
- ESR2
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背景
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Estrogen Receptor 2, Nuclear Receptor Subfamily 3 Group A Member 2 (NR3A2), Oestrogen Receptor Beta, Estrogen Receptor Beta, ER-BETA, ESTRB,ER-beta (Estrogen Receptor beta-2)
Cellular localisation: Nuclear -
分子量
- 59kDa
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基因ID
- 2100, 660607
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UniProt
- Q92731
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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