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E2F6 抗体

E2F6 适用: 人 IF, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126307
发货至: 中国
  • 抗原 See all E2F6 抗体
    E2F6 (E2F Transcription Factor 6 (E2F6))
    适用
    • 38
    • 23
    • 18
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    宿主
    • 32
    • 5
    • 1
    小鼠
    克隆类型
    • 33
    • 5
    单克隆
    标记
    • 31
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This E2F6 antibody is un-conjugated
    应用范围
    • 30
    • 12
    • 12
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.
    交叉反应 (详细)
    Human
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human E2F6 protein
    亚型
    IgG2b
    Top Product
    Discover our top product E2F6 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or Jurkat cells.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    E2F6 (E2F Transcription Factor 6 (E2F6))
    别名
    E2F6 (E2F6 产品)
    别名
    E2F-6 antibody, AI462434 antibody, E2F6b antibody, EMA antibody, E2F transcription factor 6 antibody, E2F6 antibody, E2f6 antibody
    背景
    EMA, MGC111545,E2F6
    Cellular localisation: Nucleus
    分子量
    35kDa
    基因ID
    1876, 603093
    UniProt
    O75461
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