E2F6 抗体
Quick Overview for E2F6 抗体 (ABIN7126307)
抗原
See all E2F6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.
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交叉反应 （详细）
- Human
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human E2F6 protein
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亚型
- IgG2b
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anti-E2F Transcription Factor 6 (E2F6) (Internal Region) antibody
E2F6 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 WB, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) antibodyE2F6 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F7-A9 unconjugated
anti-E2F Transcription Factor 6 (E2F6) antibodyE2F6 适用: 人 WB, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) antibodyE2F6 适用: 人, 小鼠 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (Internal Region) antibodyE2F6 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 1-281) antibodyE2F6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 6 (E2F6) (AA 43-92) antibodyE2F6 适用: 人, 小鼠, Pig, 犬, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or Jurkat cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- E2F6 (E2F Transcription Factor 6 (E2F6))
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别名
- E2F6
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背景
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EMA, MGC111545,E2F6
Cellular localisation: Nucleus -
分子量
- 35kDa
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基因ID
- 1876, 603093
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UniProt
- O75461
抗原
-
