电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IDO2 抗体 (AA 200-350)

IDO2 适用: 人 ELISA, Coat, IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126294
发货至: 中国
  • 抗原 See all IDO2 抗体
    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
    抗原表位
    • 15
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 200-350
    适用
    • 53
    • 8
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 56
    • 6
    • 1
    小鼠
    克隆类型
    • 57
    • 6
    单克隆
    标记
    • 27
    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IDO2 antibody is un-conjugated
    应用范围
    • 53
    • 23
    • 17
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa 200-350) of human IDO2 protein (exact sequence is proprietary)
    亚型
    IgG
    Top Product
    Discover our top product IDO2 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human placenta or liver.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
    别名
    IDO2 (IDO2 产品)
    背景
    3-dioxygenase 2, 3-dioxygenase-like protein 1, EC 1.13.11., INDOL 1, Indoleamine 2, Indoleamine 2,3 dioxygenase 2, Indoleamine 2,3 dioxygenase like 1 protein, Indoleamine pyrrole 2,3 dioxygenase like 1, Indoleamine-pyrrole 2,IDO2 / Indoleamine 2,3-dioxygenase 2
    Cellular localisation: Cytoplasm
    分子量
    47kDa
    基因ID
    169355, 676257
    UniProt
    Q6ZQW0
You are here:
客服