DAXX 抗体
Quick Overview for DAXX 抗体 (ABIN7126281)
抗原
See all DAXX 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
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交叉反应 （详细）
- Human
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human DAXX protein
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亚型
- IgG2
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anti-Death-Domain Associated Protein (DAXX) (AA 561-660) antibody
DAXX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 558-740) antibodyDAXX 适用: 人 WB, ICC 宿主: 小鼠 Monoclonal DAXX-01 unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 56-345) antibodyDAXX 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (C-Term) antibodyDAXX 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) antibodyDAXX 适用: 人 WB, IF, EIA 宿主: 小鼠 Monoclonal 7A11 unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer213) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (pSer495) antibodyDAXX 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 1-740) antibodyDAXX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Death-Domain Associated Protein (DAXX) (AA 580-740) antibodyDAXX 适用: 人 WB, ICC, IP 宿主: 小鼠 Monoclonal DAXX-03 unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells. Ubiquitous tissue expression.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- DAXX (Death-Domain Associated Protein (DAXX))
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别名
- DAXX
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背景
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DAP6, EAP1, BING2, SMIM40,DAXX (Transcriptional Corepressor)
Cellular localisation: Nucleus. Cytoplasm. -
分子量
- 81.37kDa
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基因ID
- 1616, 336916
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UniProt
- Q9UER7
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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