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DAXX 抗体

DAXX 适用: 人 IF, FACS, IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126280
发货至: 中国
  • 抗原 See all DAXX 抗体
    DAXX (Death-Domain Associated Protein (DAXX))
    适用
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    宿主
    • 149
    • 17
    小鼠
    克隆类型
    • 139
    • 27
    单克隆
    标记
    • 65
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    This DAXX antibody is un-conjugated
    应用范围
    • 151
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    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
    交叉反应 (详细)
    Human
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human DAXX protein
    亚型
    IgG2b
    Top Product
    Discover our top product DAXX Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or U87 cells. Ubiquitous tissue expression.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    DAXX (Death-Domain Associated Protein (DAXX))
    别名
    DAXX (DAXX 产品)
    别名
    BING2 antibody, DAP6 antibody, EAP1 antibody, LOC100226911 antibody, daxx antibody, si:dz179b20.7 antibody, wu:fd15c03 antibody, death domain associated protein antibody, Fas death domain-associated protein antibody, 28S ribosomal protein S29, mitochondrial antibody, death-domain associated protein antibody, death-associated protein 6 L homeolog antibody, DAXX antibody, Daxx antibody, LOC100226911 antibody, daxx.L antibody, daxx antibody
    背景
    DAP6, EAP1, BING2, SMIM40,DAXX (Transcriptional Corepressor)
    Cellular localisation: Nucleus. Cytoplasm.
    分子量
    81.37kDa
    基因ID
    1616, 336916
    UniProt
    Q9UER7
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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