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DAXX 抗体

This anti-DAXX antibody is a 小鼠 单克隆 antibody detecting DAXX in IF 和 FACS. Suitable for 人.
产品编号 ABIN7126278
发货至: 中国

Quick Overview for DAXX 抗体 (ABIN7126278)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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宿主

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小鼠

克隆类型

  • 132
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单克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)
  • 特异性

    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

    交叉反应 (详细)

    Human

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant full-length human DAXX protein

    亚型

    IgG2b
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or U87 cells.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    DAP6, EAP1, BING2, SMIM40,DAXX
    Cellular localisation: Nucleus. Cytosol.

    分子量

    81.37kDa

    基因ID

    1616, 336916

    UniProt

    Q9UER7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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