CD55 抗体 (AA 1-100)
Quick Overview for CD55 抗体 (AA 1-100) (ABIN7126277)
抗原
See all CD55 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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特异性
- Recognizes a single chain glycoprotein of 70 kDa, identified as CD55/DAF. It is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 may be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment (around aa1-100) of human CD55 (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat cells or human lymphocytes. Human lymph nodes and tonsils.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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别名
- CD55
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背景
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CD55, CD55 Cromer blood group system, Complement decay-accelerating factor, CROM, DAF, GPI-DAF, Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form,CD55 / Decay Accelerating Factor (DAF)
Cellular localisation: Cell Surface. Secreted. -
分子量
- 70kDa
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基因ID
- 1604, 126517
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UniProt
- P08174
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity
抗原
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