CTBP2 抗体
Quick Overview for CTBP2 抗体 (ABIN7126266)
抗原
See all CTBP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.
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交叉反应 (详细)
- Human
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human CTBP2 protein
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亚型
- IgG2b
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Molt-4 or HeLa cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
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别名
- CTBP2
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背景
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C-terminal-binding protein 2 (CTBP2), Ribeye,CTBP2 (C-terminal binding protein 2)
Cellular localisation: Nucleus. Cell junction > synapse. -
分子量
- 95.2kDa
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基因ID
- 1488, 501345
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UniProt
- P56545
抗原
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