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CD35 抗体 (AA 650-850)

CR1 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126247
发货至: 中国
  • 抗原 See all CD35 (CR1) 抗体
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 650-850
    适用
    • 107
    • 25
    • 25
    • 16
    • 16
    • 15
    • 15
    • 4
    • 3
    宿主
    • 66
    • 45
    • 3
    小鼠
    克隆类型
    • 78
    • 33
    • 3
    单克隆
    标记
    • 51
    • 11
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD35 antibody is un-conjugated
    应用范围
    • 71
    • 33
    • 31
    • 24
    • 19
    • 19
    • 18
    • 18
    • 17
    • 13
    • 13
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules.CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (within aa650-850) of human CD35 (exact sequence is proprietary)
    亚型
    IgG1
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  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Positive_Control: Follicular dendritic cells (FDC) in tonsil.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    别名
    CR1 (CR1 产品)
    背景
    C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen,CD35 / CR1 (Follicular Dendritic Cell Marker)
    Cellular localisation: Cell surface
    分子量
    224kDa
    基因ID
    1378, 334019
    UniProt
    P17927
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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