SPIC 抗体
Quick Overview for SPIC 抗体 (ABIN7126240)
抗原
See all SPIC 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The Ets transcription factor family is comprised of DNA-binding proteins that influence lymphoid development and activity and bind the consensus DNA site GGA(A/T) through a unique winged helix-turn-helix motif known as the Ets domain. Spi-B and Spi-C (also known as SPIC) are closely related Ets family members which share a conserved divergent sequence within the Ets domain that enables their binding to non-canonical AGAA sites. Spi-C is a 248 amino acid protein that localizes to the nucleus and, like other Ets family members, binds DNA as a monomer and plays a role in transcriptional regulation. Addi- tionally, Spi-C is thought to control the development of red pulp macrophages, thereby contributing to iron homeostasis and red blood cell recycling. Human Spi-C shares 65 % amino acid identity with its mouse counterpart, suggesting a conserved role between species.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human SPIC protein
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亚型
- IgG2b
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anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (Internal Region) antibody
SPIC 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (AA 1-248) antibodySPIC 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (C-Term) antibodySPIC 适用: 人, 小鼠, Cow, 马, 犬, 豚鼠, 大鼠, 兔, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (Internal Region) antibodySPIC 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) antibodySPIC 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (N-Term) antibodySPIC 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (AA 148-197) antibodySPIC 适用: 人, 马, 犬, 豚鼠, 大鼠, 兔, 猴, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (N-Term) antibodySPIC 适用: 人, Cow, 马, 犬, 豚鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (C-Term) antibodySPIC 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC) (N-Term) antibodySPIC 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat or Raji cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
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别名
- SPIC
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背景
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AU019198, C76795, MGC40611, MGC80555, Prf, Pu.1 related factor, Spi C, Spi C transcription factor, Spi-C transcription factor (Spi-1/PU.1 related),SPI-C / Transcription factor Spi-C
Cellular localisation: Nucleus -
分子量
- 29kDa
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基因ID
- 121599, 577097
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UniProt
- Q8N5J4
抗原
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