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SPIC 抗体 (C-Term)

SPIC 适用: 人, 小鼠, Cow, 马, 犬, 豚鼠, 大鼠, 兔, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779513
发货至: 中国
  • 抗原 See all SPIC 抗体
    SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
    抗原表位
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 25
    • 11
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, Cow, 马, 犬, 豚鼠, 大鼠, 兔, Pig, 斑马鱼
    宿主
    • 31
    • 1
    克隆类型
    • 31
    • 1
    多克隆
    标记
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPIC antibody is un-conjugated
    应用范围
    • 15
    • 15
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI
    预测反应
    Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    产品特性
    This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product SPIC Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 248 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zhu, Schweitzer, Romer, Sulentic, DeKoter: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." in: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).

  • 抗原
    SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))
    别名
    SPIC (SPIC 产品)
    别名
    SPI-C antibody, AU019198 antibody, C76795 antibody, Prf antibody, Spi-C antibody, zgc:101790 antibody, spi-c antibody, spic antibody, Spi-C transcription factor antibody, transcription factor Spi-C-like antibody, Spi-C transcription factor (Spi-1/PU.1 related) antibody, Spi-C transcription factor (Spi-1/PU.1 related) S homeolog antibody, SPIC antibody, LOC100349167 antibody, Spic antibody, spic antibody, spic.S antibody
    背景
    SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC Regulates VCAM1 gene expression.
    Alias Symbols: MGC40611, SPI-C
    Protein Interaction Partner: APP,
    Protein Size: 248
    分子量
    29 kDa
    基因ID
    121599
    NCBI登录号
    NM_152323, NP_689536
    UniProt
    Q8N5J4
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