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Recombinant Podoplanin 抗体 (AA 1-100)

This anti-Podoplanin antibody is a 兔 单克隆 antibody detecting Podoplanin in ELISA, IF, IHC (f) 和 Coat. Suitable for 人.
产品编号 ABIN7126197
发货至: 中国

Quick Overview for Recombinant Podoplanin 抗体 (AA 1-100) (ABIN7126197)

抗原

See all Podoplanin (PDPN) 抗体
Podoplanin (PDPN)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Podoplanin antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
  • 抗原表位

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    AA 1-100

    特异性

    It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas,Kaposi sarcomas,and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Synthetic peptide corresponding to residues within aa1-100 of Podoplanin

    亚型

    IgG
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human tonsil, cervical or lung carcinoma tissues.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Podoplanin (PDPN)

    别名

    PDPN

    背景

    Aggrus, Glycoprotein 36 KD, Glycoprotein 36, gp36, GP38, GP40, HT1A1, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein T1A 2, OTS8,Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)
    Cellular localisation: Cell Surface

    分子量

    17kDa

    基因ID

    10630, 468675

    UniProt

    Q86YL7

    途径

    Dicarboxylic Acid Transport
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