DMRT2 抗体
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Quick Overview for DMRT2 抗体 (ABIN7504176)
抗原
See all DMRT2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human DMRT2 protein
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亚型
- IgG2b
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anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (N-Term) antibody
DMRT2 适用: 人, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (AA 222-256) antibodyDMRT2 适用: 人 WB 宿主: 兔 Polyclonal RB53654 unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (AA 357-392) antibodyDMRT2 适用: 人 WB 宿主: 兔 Polyclonal RB53639 unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (C-Term) antibodyVerified DMRT2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (AA 99-190) antibodyDMRT2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (AA 461-510) antibodyDMRT2 适用: 人, 兔, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (AA 143-192) antibodyDMRT2 适用: 人, 兔, Cow, 犬, 豚鼠, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2) (N-Term) antibodyDMRT2 适用: 人, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: HeLa or MCF-7 cells.
Known Application: Flow Cytometry (1-2 μg/million cells), ,Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
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有效期
- 24 months
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- DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))
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别名
- DMRT2
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背景
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Doublesex and mab-3 related transcription factor 2, doublesex-like 2 protein (DSXL-2), terra like protein antibody,DMRT2 (Transcription Factor)
Cellular localisation: Nucleus -
分子量
- 62kDa
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基因ID
- 10655, 59506
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UniProt
- Q9Y5R5
抗原
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