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Recombinant CDX2 抗体

This anti-CDX2 antibody is a 小鼠 单克隆 antibody detecting CDX2 in IHC (f). Suitable for 人 和 Synthetic.
产品编号 ABIN7504158
发货至: 中国

Quick Overview for Recombinant CDX2 抗体 (ABIN7504158)

抗原

See all CDX2 抗体
CDX2 (Caudal Type Homeobox 2 (CDX2))

抗体类型

Recombinant Antibody

适用

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人, Synthetic

宿主

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小鼠

克隆类型

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单克隆

标记

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This CDX2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 特异性

    The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

    交叉反应 (详细)

    Human.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragments and synthetic peptides from human CDX2 protein (exact sequences are proprietary)

    亚型

    IgG1
  • 应用备注

    Positive Control: HT29 cells. Human colon carcinoma

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

    有效期

    24 months
  • 抗原

    CDX2 (Caudal Type Homeobox 2 (CDX2))

    别名

    CDX2

    背景

    Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2,CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)
    Cellular localisation: Nuclear

    分子量

    40kDa

    基因ID

    1045, 174249

    UniProt

    Q99626

    途径

    Peptide Hormone Metabolism, Stem Cell Maintenance
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