IRF9 抗体
Quick Overview for IRF9 抗体 (ABIN7504160)
抗原
See all IRF9 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
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交叉反应 （详细）
- Human
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human IRF9 protein
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亚型
- IgG2a
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anti-Interferon Regulatory Factor 9 (IRF9) (AA 75-104) antibody
IRF9 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-393) antibodyIRF9 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 101-200) antibodyIRF9 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-393) antibodyIRF9 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 171-393) antibodyIRF9 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 75-104) antibodyIRF9 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB19229 unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 44-180) antibodyIRF9 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-393) antibodyIRF9 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (AA 1-394) antibodyIRF9 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Interferon Regulatory Factor 9 (IRF9) (N-Term) antibodyIRF9 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: MCF-7, Jurkat or K562 cells.
Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
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有效期
- 24 months
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- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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别名
- IRF9
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背景
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IFN alpha responsive transcription factor subunit, Interferon regulatory factor 9, Interferon-stimulated gene factor 3 gamma, interferon-stimulated transcription factor 3, gamma 48 kDa, IRF-9, ISGF-3 gamma, ISGF3 p48 subunit, ISGF3G, p48, Transcriptional regulator ISGF3 subunit gamma,Interferon regulatory factor 9 / IRF-9
Cellular localisation: Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta. -
分子量
- 43.34kDa
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基因ID
- 10379, 1706
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UniProt
- Q00978
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
抗原
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