IRF9 抗体 (N-Term)
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北京 101111
Quick Overview for IRF9 抗体 (N-Term) (ABIN2777226)
抗原
See all IRF9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- ISGF3G Antibody - N-terminal region
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序列
- PWKHAGKQDF REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against ISGF3G. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ISGF3G
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8103270
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape." in: Nature medicine, Vol. 18, Issue 8, pp. 1224-31, (2013) (PubMed).
: "Structural basis of core promoter recognition in a primitive eukaryote." in: Cell, Vol. 115, Issue 4, pp. 413-24, (2003) (PubMed).
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- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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别名
- ISGF3G
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背景
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Background Information: ISGF3G functions to recruit RNA polymerase II to the promoter of interferon-stimulated genes and requires histone deacetylases. Defects in ISGF3 can cause resistance to IFN-.(2a) treatment.
Gene Name: Interferon regulatory factor 9
Alternative Symbols: p48, IRF-9, ISGF3, ISGF3G
Protein Name: Interferon regulatory factor 9
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分子量
- 44 kDa
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基因ID
- 10379
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NCBI登录号
- NP_006075
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UniProt
- Q00978
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途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
抗原
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