MEF2B 抗体
Quick Overview for MEF2B 抗体 (ABIN7504178)
抗原
See all MEF2B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant full-length human MEF2B protein
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亚型
- IgG2a
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anti-Myocyte Enhancer Factor 2B (MEF2B) (AA 165-235) antibody
MEF2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B5 unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (Internal Region) antibodyMEF2B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (Internal Region) antibodyMEF2B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (AA 51-100) antibodyMEF2B 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (AA 1-365) antibodyMEF2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (C-Term) antibodyMEF2B 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (N-Term) antibodyMEF2B 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (AA 1-100) antibodyMEF2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (C-Term) antibodyMEF2B 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2B (MEF2B) (N-Term) antibodyMEF2B 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 豚鼠, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: HeLa or Ramos cells.
Known Application: Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Western Blot (1-2 μg/mL),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
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有效期
- 24 months
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- MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
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别名
- MEF2B
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背景
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MADS box transcription enhancer factor 2, MDS1 EVI1, Mef2b, Myocyte enhancer factor 2B, Myocyte-specific enhancer factor 2B, PRDM3, RSRFR2, Serum response factor like protein 2, XMEF2,MEF2B (Transcriptional Activator)
Cellular localisation: Nucleus. -
分子量
- 160kDa
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基因ID
- 100271849, 4207, 153629
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UniProt
- Q02080
抗原
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