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MEF2B 抗体

MEF2B 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385666
发货至: 中国
  • 抗原 See all MEF2B 抗体
    MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 27
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    克隆类型
    • 28
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    多克隆
    标记
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    This MEF2B antibody is un-conjugated
    应用范围
    • 31
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    • 3
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    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MEF2B
    亚型
    IgG
    Top Product
    Discover our top product MEF2B Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MEF2B (Myocyte Enhancer Factor 2B (MEF2B))
    别名
    MEF2B (MEF2B 产品)
    别名
    si:ch211-125m10.1 antibody, AI451606 antibody, RSRFR2 antibody, myocyte enhancer factor 2b antibody, myocyte enhancer factor 2B antibody, mef2b antibody, MEF2B antibody, Mef2b antibody
    背景

    Synonyms: PRDM3, MADS box transcription enhancer factor 2, MDS1 EVI1, Mef2b, MEF2B_HUMAN, MEF-2B, myocyte enhancer factor 2B, myocyte specic enhancer factor 2B, Myocyte-specic enhancer factor 2B, RSRFR2, serum response factor like protein 2, Serum response factor-like protein 2, XMEF2.

    Background: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

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