ZBTB7B 抗体
Quick Overview for ZBTB7B 抗体 (ABIN7120925)
抗原
See all ZBTB7B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ZBTB7B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- zinc finger and BTB domain containing 7B
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IF: 1:10-1:100, IP: 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))
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别名
- ZBTB7B
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背景
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Synonyms: Zinc finger and BTB domain-containing protein 7B|Krueppel-related zinc finger protein cKrox (hcKrox)|T-helper-inducing POZ/Krueppel-like factor|Zinc finger and BTB domain-containing protein 15|Zinc finger protein 67 homolog (Zfp-67)|Zinc finger protein 857B|Zinc finger protein Th-POK|ZBTB7B|ZBTB15|ZFP67|ZNF857B
Background: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors(thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes(By similarity).
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分子量
- 58 kDa
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基因ID
- 51043
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UniProt
- O15156
抗原
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