WWOX 抗体
Quick Overview for WWOX 抗体 (ABIN7120868)
抗原
See all WWOX 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- WWOX antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- WW domain containing oxidoreductase
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- WWOX (WW Domain Containing Oxidoreductase (WWOX))
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别名
- WWOX
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背景
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Synonyms: WW domain-containing oxidoreductase|Fragile site FRA16D oxidoreductase|Short chain dehydrogenase/reductase family 41C member 1|WWOX|FOR|SDR41C1|WOX1
Background: Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development(By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor(TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
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分子量
- 47 kDa
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基因ID
- 51741
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UniProt
- Q9NZC7
抗原
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