WWP2 抗体
Quick Overview for WWP2 抗体 (ABIN7120867)
抗原
See all WWP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- WWP2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- WW domain containing E3 ubiquitin protein ligase 2
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亚型
- IgG
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anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (Middle Region) antibody
WWP2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 601-870) antibodyWWP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 1-335) antibodyWWP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (N-Term) antibodyWWP2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 猴, Hamster, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (Middle Region) antibodyWWP2 适用: 人, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 145-367) antibodyWWP2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 218-252), (N-Term) antibodyWWP2 适用: 人 WB 宿主: 兔 Polyclonal RB51426 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 1-110) antibodyWWP2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (C-Term) antibodyWWP2 适用: 人, 犬, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 323-372) antibodyWWP2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 猴, Hamster, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:200-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
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别名
- WWP2
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背景
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Synonyms: NEDD4-like E3 ubiquitin-protein ligase WWP2|Atrophin-1-interacting protein 2 (AIP2)|HECT-type E3 ubiquitin transferase WWP2|WW domain-containing protein 2|WWP2
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation, in embryonic stem cells(ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation, in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2, the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
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分子量
- 120 kDa
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基因ID
- 11060
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UniProt
- O00308
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途径
- Negative Regulation of Transporter Activity
抗原
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