GPR177/WLS 抗体 (AA 43-234)
Quick Overview for GPR177/WLS 抗体 (AA 43-234) (ABIN7120857)
抗原
See all GPR177/WLS (WLS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 43-234
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原理
- WLS antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 43-234aa
Immunogen: G protein-coupled receptor 177
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亚型
- IgG
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anti-Wntless Homolog (WLS) (AA 123-232) antibody
WLS 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wntless Homolog (WLS) (N-Term) antibodyWLS 适用: 人, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wntless Homolog (WLS) (N-Term) antibodyWLS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wntless Homolog (WLS) (AA 53-102) antibodyWLS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Wntless Homolog (WLS) antibodyWLS 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wntless Homolog (WLS) (Middle Region) antibodyWLS 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- GPR177/WLS (WLS) (Wntless Homolog (WLS))
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别名
- WLS
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背景
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Synonyms: Protein wntless homolog|Integral membrane protein GPR177|Protein evenness interrupted homolog (EVI)|Putative NF-kappa-B-activating protein 373|WLS|C1orf139|GPR177
Background: GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736).
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分子量
- 46-62 kDa
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基因ID
- 79971
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UniProt
- Q5T9L3
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途径
- WNT signaling
抗原
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