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WDR1 抗体

This anti-WDR1 antibody is a 兔 多克隆 antibody detecting WDR1 in WB, IHC, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120810
发货至: 中国

Quick Overview for WDR1 抗体 (ABIN7120810)

抗原

See all WDR1 抗体
WDR1 (WD Repeat Domain 1 (WDR1))

适用

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人, 小鼠, 大鼠

宿主

  • 37
  • 1
  • 1

克隆类型

  • 34
  • 5
多克隆

标记

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This WDR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    WD repeat domain 1

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    WDR1 (WD Repeat Domain 1 (WDR1))

    别名

    WDR1

    背景

    Synonyms:Actin interacting protein 1, AIP1, NORI 1, WD repeat containing protein 1, WD repeat domain 1, WDR1 Background:Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins(PubMed:15629458). Enhances cofilin-mediated actin severing(By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions(PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance(By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity(PCP) during follicular epithelium development and for cell shape changes during PCP, the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension(By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt(PubMed:25792565).

    分子量

    66 kDa

    基因ID

    9948

    UniProt

    O75083

    途径

    Sensory Perception of Sound
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