WDR1 抗体
Quick Overview for WDR1 抗体 (ABIN7120810)
抗原
See all WDR1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- WDR1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- WD repeat domain 1
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亚型
- IgG
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应用备注
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- WDR1 (WD Repeat Domain 1 (WDR1))
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别名
- WDR1
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背景
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Synonyms: WD repeat-containing protein 1|Actin-interacting protein 1 (AIP1)|NORI-1|WDR1
Background: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins(PubMed:15629458). Enhances cofilin-mediated actin severing(By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions(PubMed:18494608). Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance(By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity(PCP) during follicular epithelium development and for cell shape changes during PCP, the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension(By similarity). Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt(PubMed:25792565).
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分子量
- 66 kDa
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基因ID
- 9948
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UniProt
- O75083
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途径
- Sensory Perception of Sound
抗原
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