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Vitamin D Receptor 抗体

The 兔 多克隆 anti-Vitamin D Receptor antibody is suitable to detect Vitamin D Receptor in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN7120778
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Vitamin D Receptor 抗体 (ABIN7120778)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

  • 105
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  • 50
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  • 1
人, 小鼠, 大鼠

宿主

  • 112
  • 11
  • 1
  • 1

克隆类型

  • 95
  • 30
多克隆

标记

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  • 3
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  • 2
  • 2
  • 2
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  • 2
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  • 1
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This Vitamin D Receptor antibody is un-conjugated

应用范围

  • 98
  • 33
  • 26
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  • 7
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  • 2
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    VDR antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    vitamin D (1, 25- dihydroxyvitamin D3) receptor

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    Vitamin D Receptor (VDR)

    别名

    VDR

    物质类

    Chemical

    背景

    Synonyms: Vitamin D3 receptor (VDR)|1,25-dihydroxyvitamin D3 receptor|Nuclear receptor subfamily 1 group I member 1|VDR|NR1I1

    Background: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.

    分子量

    43 kDa

    基因ID

    7421

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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