Vimentin 抗体
Quick Overview for Vimentin 抗体 (ABIN7120771)
抗原
See all Vimentin (VIM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - Protein A+G purification
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纯度
 - ≥95 % as determined by SDS-PAGE
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免疫原
 - vimentin
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亚型
 - IgG1
 
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应用备注
 - WB: 1:1000-1:10000, IHC: 1:200-1:2000, IF: 1:20-1:200
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
 - 12 months
 
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- Vimentin (VIM)
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别名
 - Vimentin
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背景
 - Synonyms:FLJ36605, VIM, Vimentin Background:Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha(TNFA, 191160) and inhibited by the antiinflammatory cytokine IL10(124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
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分子量
 - 55 kDa
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UniProt
 - P08670
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途径
 - Caspase Cascade in Apoptosis
 
抗原
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