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UBE2C 抗体

The 小鼠 单克隆 anti-UBE2C antibody is suitable to detect UBE2C in samples from 人. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN7120541
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for UBE2C 抗体 (ABIN7120541)

抗原

See all UBE2C 抗体
UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This UBE2C antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

7E3
  • 原理

    UBE2C antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ubiquitin-conjugating enzyme E2C

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

    别名

    UBE2C

    背景

    Synonyms: Ubiquitin-conjugating enzyme E2 C|(E3-independent) E2 ubiquitin-conjugating enzyme C|E2 ubiquitin-conjugating enzyme C|UbcH10|Ubiquitin carrier protein C|Ubiquitin-protein ligase C|UBE2C|UBCH10

    Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

    分子量

    17 kDa

    基因ID

    11065

    UniProt

    O00762

    途径

    Ubiquitin Proteasome Pathway
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