UBE2C 抗体
Quick Overview for UBE2C 抗体 (ABIN7120541)
抗原
See all UBE2C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- UBE2C antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin-conjugating enzyme E2C
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亚型
- IgG1
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
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别名
- UBE2C
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背景
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Synonyms: Ubiquitin-conjugating enzyme E2 C|(E3-independent) E2 ubiquitin-conjugating enzyme C|E2 ubiquitin-conjugating enzyme C|UbcH10|Ubiquitin carrier protein C|Ubiquitin-protein ligase C|UBE2C|UBCH10
Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
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分子量
- 17 kDa
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基因ID
- 11065
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UniProt
- O00762
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途径
- Ubiquitin Proteasome Pathway
抗原
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