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USP5 抗体

The 小鼠 单克隆 anti-USP5 antibody is suitable to detect USP5 in samples from 人. It has been validated for WB 和 ELISA.
产品编号 ABIN7120529
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for USP5 抗体 (ABIN7120529)

抗原

See all USP5 抗体
USP5 (Ubiquitin Specific Peptidase 5 (USP5))

适用

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宿主

  • 34
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小鼠

克隆类型

  • 33
  • 9
单克隆

标记

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This USP5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

6G1
  • 原理

    USP5 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ubiquitin specific peptidase 5(isopeptidase T)

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    USP5 (Ubiquitin Specific Peptidase 5 (USP5))

    别名

    USP5

    背景

    Synonyms: Ubiquitin carboxyl-terminal hydrolase 5|Deubiquitinating enzyme 5|Isopeptidase T|Ubiquitin thioesterase 5|Ubiquitin-specific-processing protease 5|USP5|ISOT

    Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

    分子量

    93 kDa

    基因ID

    8078

    UniProt

    P45974
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