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USP5 抗体

This anti-USP5 antibody is a 兔 多克隆 antibody detecting USP5 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7120527
发货至: 中国

Quick Overview for USP5 抗体 (ABIN7120527)

抗原

See all USP5 抗体
USP5 (Ubiquitin Specific Peptidase 5 (USP5))

适用

  • 41
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 33
  • 9

克隆类型

  • 33
  • 9
多克隆

标记

  • 27
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This USP5 antibody is un-conjugated

应用范围

  • 28
  • 18
  • 10
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ubiquitin specific peptidase 5(isopeptidase T)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    USP5 (Ubiquitin Specific Peptidase 5 (USP5))

    别名

    USP5

    背景

    Synonyms:Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5 Background:Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

    分子量

    93 kDa

    基因ID

    8078

    UniProt

    P45974
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