USP37 抗体
Quick Overview for USP37 抗体 (ABIN7120518)
抗原
See all USP37 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- USP37 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin specific peptidase 37
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- USP37 (Ubiquitin Specific Peptidase 37 (USP37))
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别名
- USP37
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 37|Deubiquitinating enzyme 37|Ubiquitin thioesterase 37|Ubiquitin-specific-processing protease 37|USP37|KIAA1594
Background: Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).
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分子量
- 110 kDa, 70 kDa
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基因ID
- 57695
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UniProt
- Q86T82
抗原
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