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USP34 抗体

The 兔 多克隆 anti-USP34 antibody (ABIN7120515) specifically detects USP34 in WB, ELISA 和 IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7120515
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for USP34 抗体 (ABIN7120515)

抗原

See all USP34 抗体
USP34 (Ubiquitin Specific Peptidase 34 (USP34))

适用

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人, 小鼠

宿主

  • 13
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克隆类型

  • 14
  • 1
多克隆

标记

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This USP34 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 原理

    USP34 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    ubiquitin specific peptidase 34

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    USP34 (Ubiquitin Specific Peptidase 34 (USP34))

    别名

    USP34

    背景

    Synonyms: Ubiquitin carboxyl-terminal hydrolase 34|Deubiquitinating enzyme 34|Ubiquitin thioesterase 34|Ubiquitin-specific-processing protease 34|USP34|KIAA0570|KIAA0729

    Background: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.

    分子量

    47 kDa

    基因ID

    9736

    UniProt

    Q70CQ2
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