USP34 抗体
Quick Overview for USP34 抗体 (ABIN7120515)
抗原
See all USP34 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- USP34 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin specific peptidase 34
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- USP34 (Ubiquitin Specific Peptidase 34 (USP34))
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别名
- USP34
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase 34|Deubiquitinating enzyme 34|Ubiquitin thioesterase 34|Ubiquitin-specific-processing protease 34|USP34|KIAA0570|KIAA0729
Background: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
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分子量
- 47 kDa
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基因ID
- 9736
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UniProt
- Q70CQ2
抗原
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