Urm1 抗体
Quick Overview for Urm1 抗体 (ABIN7120488)
抗原
See all Urm1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- URM1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ubiquitin related modifier 1 homolog
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亚型
- IgG
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anti-Ubiquitin Related Modifier 1 (Urm1) antibody
Urm1 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) (Internal Region) antibodyUrm1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) (AA 1-63) antibodyUrm1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) antibodyUrm1 适用: Saccharomyces cerevisiae WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:5000, IHC:1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Urm1 (Ubiquitin Related Modifier 1 (Urm1))
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别名
- URM1
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背景
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Synonyms: Ubiquitin-related modifier 1|URM1|C9orf74
Background: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated(-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein(UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
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分子量
- 11 kDa
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基因ID
- 81605
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UniProt
- Q9BTM9
抗原
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