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Urm1 抗体 (Internal Region)

Urm1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265904
发货至: 中国
  • 抗原 See all Urm1 抗体
    Urm1 (Ubiquitin Related Modifier 1 (Urm1))
    抗原表位
    • 7
    • 2
    • 1
    Internal Region
    适用
    • 21
    • 9
    • 9
    • 1
    人, 大鼠, 小鼠
    宿主
    • 21
    • 2
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Urm1 antibody is un-conjugated
    应用范围
    • 15
    • 11
    • 10
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    URM1 Antibody detects endogenous levels of total URM1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human URM1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product Urm1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Urm1 (Ubiquitin Related Modifier 1 (Urm1))
    别名
    URM1 (Urm1 产品)
    别名
    RGD1306599 antibody, C9orf74 antibody, 2900073H19Rik antibody, ubiquitin related modifier 1 antibody, ubiquitin related modifier antibody, ubiquitin-related modifier antibody, Ubiquitin-related modifier 1 homolog antibody, Urm1 antibody, LOC733109 antibody, URM1 antibody
    背景

    Description: Acts as a sulfur carrier required for 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm5S2U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.

    Gene: URM1

    分子量
    11 kDa
    基因ID
    81605
    UniProt
    Q9BTM9
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