TDP2 抗体
Quick Overview for TDP2 抗体 (ABIN7120444)
抗原
See all TDP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TDP2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- TRAF and TNF receptor associated protein
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))
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别名
- TDP2
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背景
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Synonyms: Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2, hTDP2)|5'-tyrosyl-DNA phosphodiesterase (5'-Tyr-DNA phosphodiesterase)|ETS1-associated protein 2|ETS1-associated protein II (EAPII)|TRAF and TNF receptor-associated protein|Tyrosyl-RNA phosphodiesterase|VPg unlinkase|TDP2|EAP2|TTRAP
Background: TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regulator of ETS1 and inhibit nuclear factor-kappa-B activation.
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分子量
- 44 kDa
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UniProt
- O95551
抗原
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