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p63 抗体

This anti-p63 antibody is a 小鼠 单克隆 antibody detecting p63 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7120423
发货至: 中国

Quick Overview for p63 抗体 (ABIN7120423)

抗原

See all p63 (TP63) 抗体
p63 (TP63) (Tumor Protein P63 (TP63))

适用

  • 64
  • 25
  • 20
  • 5
  • 2
  • 2

宿主

  • 49
  • 22
  • 1
小鼠

克隆类型

  • 42
  • 30
单克隆

标记

  • 62
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This p63 antibody is un-conjugated

应用范围

  • 45
  • 30
  • 25
  • 14
  • 14
  • 10
  • 9
  • 9
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  • 2
  • 1
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Western Blotting (WB), ELISA

克隆位点

2A3
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    tumor protein p63

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    p63 (TP63) (Tumor Protein P63 (TP63))

    别名

    TP63

    背景

    Synonyms:KET, P63, P73H, P73L, TP73L Background:Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

    分子量

    68 kDa

    基因ID

    8626

    UniProt

    Q9H3D4
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