TBCD 抗体
Quick Overview for TBCD 抗体 (ABIN7120359)
抗原
See all TBCD 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TBCD antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- tubulin folding cofactor D
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亚型
- IgG
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anti-Tubulin Folding Cofactor D (TBCD) (AA 2-96) antibody
TBCD 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor D (TBCD) (AA 1-623) antibodyTBCD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tubulin Folding Cofactor D (TBCD) (AA 299-348) antibodyTBCD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor D (TBCD) (N-Term) antibodyTBCD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tubulin Folding Cofactor D (TBCD) (N-Term) antibodyTBCD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TBCD (Tubulin Folding Cofactor D (TBCD))
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别名
- TBCD
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背景
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Synonyms: Tubulin-specific chaperone D|Beta-tubulin cofactor D (tfcD)|SSD-1|Tubulin-folding cofactor D|TBCD|KIAA0988|SSD1|TFCD
Background: Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
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分子量
- 130 kDa
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基因ID
- 6904
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UniProt
- Q9BTW9
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途径
- Cell-Cell Junction Organization
抗原
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