TIMM8A
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
应用备注
WB: 1:500-1:2000
限制
仅限研究用
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
有效期
12 months
抗原
TIMM8A/DDP (TIMM8A)
(Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
别名
TIMM8A
背景
Synonyms:DDP, DDP1, TIM8A Background:Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery(SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.