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TPX2 抗体

TPX2 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120029
发货至: 中国
  • 抗原 See all TPX2 抗体
    TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
    适用
    • 60
    • 34
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 60
    • 15
    克隆类型
    • 58
    • 17
    多克隆
    标记
    • 36
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This TPX2 antibody is un-conjugated
    应用范围
    • 65
    • 33
    • 13
    • 13
    • 13
    • 11
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    TPX2, microtubule-associated, homolog(Xenopus laevis)
    亚型
    IgG
    Top Product
    Discover our top product TPX2 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
    别名
    TPX2 (TPX2 产品)
    背景
    Synonyms:C20orf1, C20orf2, DIL2, HCA519 Background:Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules(PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation(PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha(PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation(PubMed:26165940).
    分子量
    100 kDa
    UniProt
    Q9ULW0
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